There are 13 Trustees of the U. S. Conference of Mayors, who serve as leaders in the organization. Each Mayor who is a Trustee is also on the Executive Committee, although the Executive Committee consists of persons who are not Trustees, the exception being Past USCM Presidents.

• Mayor J. Christian Bollwage, Elizabeth, NJ
• Mayor James Brainard, Carmel, IN
• Mayor Michael Coleman, Columbus, OH
• Mayor Mick Cornett, Oklahoma City, OK
• Mayor T.M. Franklin Cownie, Des Moines, IA
• Mayor Bob Foster, Long Beach, CA
• Mayor Patrick Henry Hays, North Little Rock, AR
• Mayor Kevin Johnson, Sacramento, CA
• Mayor Brenda L. Lawrence, Southfield, MI
• Mayor John R. Marks, III, Tallahassee, FL
• Mayor Arlene J. Mulder, Arlington Heights, IL
• Mayor Stephanie C. Rawlings-Blake, Baltimore, MD
• Mayor Ashley Swearengin, Fresno, CA